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Female Infertility

Summary

Infertility means not being able to get pregnant after at least one year of trying (or 6 months if the woman is over age 35). If a woman keeps having miscarriages, it is also called infertility. Female infertility can result from age, physical problems, hormone problems, and lifestyle or environmental factors.

Most cases of infertility in women result from problems with producing eggs. In primary ovarian insufficiency, the ovaries stop functioning before natural menopause. In polycystic ovary syndrome (PCOS), the ovaries may not release an egg regularly or they may not release a healthy egg.

About a third of the time, infertility is because of a problem with the woman. One third of the time, it is a problem with the man. Sometimes no cause can be found.

If you think you might be infertile, see your doctor. There are tests that may tell if you have fertility problems. When it is possible to find the cause, treatments may include medicines, surgery, or assisted reproductive technologies. Happily, many couples treated for infertility are able to have babies.

Dept. of Health and Human Services Office on Women's Health

Start Here

  • Infertility (Department of Health and Human Services, Office on Women's Health) Also in Spanish
  • Reproductive Infertility (Endocrine Society)
  • Trying to Conceive (Department of Health and Human Services, Office on Women's Health) Also in Spanish
  • What Are Some Causes of Infertility? From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Diagnosis and Tests

Treatments and Therapies

  • Assisted Reproductive Technology: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Fertility Treatments for Females From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish
  • Intrauterine Insemination (IUI) (Mayo Foundation for Medical Education and Research) Also in Spanish
  • Medications for Inducing Ovulation (American Society for Reproductive Medicine) Also in Spanish
  • Ovarian Drilling for Infertility (American Society for Reproductive Medicine) - PDF
  • Treatments for Diseases that Cause Infertility From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Living With

  • Weight and Fertility (American Society for Reproductive Medicine) Also in Spanish

Related Issues

  • Diethylstilbestrol (DES) Exposure and Cancer From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Fertility Issues in Girls and Women with Cancer From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Side Effects of Injectable Fertility Drugs (Gonadotropins) (American Society for Reproductive Medicine)

Specifics

  • Endometriosis: Does It Cause Infertility? (American Society for Reproductive Medicine) - PDF Also in Spanish
  • Fallopian Tubes: Is Pregnancy Possible with Only One? (Mayo Foundation for Medical Education and Research) Also in Spanish
  • What Age-Related Factors May Be Involved with Infertility in Females and Males? From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Genetics

Videos and Tutorials

Clinical Trials

  • ClinicalTrials.gov: Infertility, Female From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: The effects of hydroxychloroquine on pregnancy outcomes in infertile women: a...
  • Article: Letrozole cotreatment improves the follicular output rate in high-body-mass-index women with...
  • Article: Inflammatory bowel disease can reduce ovarian reserve function in women: A...
  • Female Infertility -- see more articles

Reference Desk

  • Female Reproductive System From the National Institutes of Health (National Cancer Institute)

Find an Expert

  • Department of Health and Human Services, Office on Women's Health Also in Spanish
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development From the National Institutes of Health Also in Spanish
  • Find an Ob-Gyn (American College of Obstetricians and Gynecologists)

Patient Handouts

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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